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| Time | Talks |
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| All day |
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| 12:00 pm |
12:00pm - 01:00pm
Darin Dougherty - Neurotherapeutic Interventions in PsychiatryDarin Dougherty, MD, MSc
MGH Abstract: While the majority of patients with psychiatric illness respond to conventional treatments (e.g., psychotherapy, pharmacotherapy), a minority do not and are considered treatment-resistant. For these patients, neurotherapeutic interventions may be warranted. Neurotherapeutic interventions refer to surgical and/or device-related treatments and include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ablative limbic system surgery (e.g., anterior cingulotomy, limbic leukotomy), epidural cortical stimulation (EpCS), and deep brain stimulation (DBS). I will review our experience with each of these procedures at MGH and will include results from concurrent imaging studies regarding the pathophysiology of these illnesses, changes associated with these interventions, and the potential utility of using pretreatment neuroimaging to predict subsequent response. I will conclude with a review of possible future directions within the field of psychiatric neurotherapeutics including targeted delivery of neurotransmitters or neurotrophic growth factors and optogenetics. |
